Scientia Sinica

60 SCIENTIA SINICA Vol. V

1,2,3,4,9,10,11,12-octahydrophenanthrenes was obtained. From each of these two mixtures of the diastereoisomeric keto esters, by use of acetone-petroleum ether mixed solvents, only the least soluble diastereoisomer was obtained pure.

3. By means of Reformatsky reaction between methyl bromoacetate and d-\-keto-2-methyl - 2 - carbomethoxy - 7 - methoxy-1, 2, 3, 4, 9, 10, 11, 12-octahy drophenanthrene, methyl d-\-hydroxy-2-methyl-2-carbomethoxy-7-methoxy1,2,3,4,9,10,11,12-octahydrophenanthrene-l-acetate was obtained. In the same way, from the pure diastereoisomeric /-1-keto-2-methyl-2-carbomethoxy-7methoxy-1,2,3,4,9,10,11,12-octahydrophenanthrene, methyl /-1-hydroxy-2-methyl2-carbomethoxy-/-methoxy-l, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-L-acetate was obtained.

REFERENCES

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