Chinese Journal of Physiology

TABLE 4

Comparison of the maximal effects of small doses of ephedrine and pseudoephedrine upon the nasal volume and blood pressure of dogs

ose | Increases in nasal volume Increases in blood pressure ae Order of injections

per kg mg

Maximal |) Aftesae (2h Ephedrine| 2. Ps-ephed.| Maximal After 3 |1. Ephedrine} 2. Ps-ephed. | | ; | min, |2. Ps-epned.|1, Ephedrine effe min, 2. Ps-ephed.| 1. Ephedrine

| Dog @,128kg | mm* | mam Eg mm Hy | J. Ephedrine 7 AO 0.37 ) 16 1.68 2%. Ps-ephedrine JO . | A | 3. Ephedrine 18 | 8 |

Dog $, 0.5 kg

x 0

. oO | 2. Ephedrine 13 10 1G 10 | 3, Ps-ephedrine 3 3 | 4 2

|

J, Ps-ephedrine 5 0.388 8 2 2,00 0,50

*The number of mm is taken from the measurement of the distance between the original level and the tangent of the curve, which represented the change of nasal volume.

THE EPHEDRINES ON N

ASA

\L MUCOSA

107